The Effect of Sodium Citrate and Reduced Glutathione (Gsh) on Arginase From Human Fibriod Tissue

The Effect of Sodium Citrate and Reduced Glutathione (Gsh) on Arginase From Human Fibriod Tissue

The Effect of Sodium Citrate and Reduced Glutathione (Gsh) on Arginase From Human Fibriod Tissue

 

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Abstract on The Effect of Sodium Citrate and Reduced Glutathione (Gsh) on Arginase From Human Fibriod Tissue

The research is aimed at investigating the effect of sodium citrate and reduced glutathione (GSH) on arginase from human fibriod tissue.

The research shows that arginase enzyme which was partially purified was found to have a specific interaction with its substrate.

The study shows that varying the substrate concentration at constant volume of Sodium citrate and Reduced glutathione (GSH) resulted into an Un-competitive inhibition and Competitive inhibition of enzymes respectively.

The results obtained from this study shows that the inhibition nature of arginase by different inhibitors of enzymes gives a promising approach to abnormal arginase activities in cell proliferation of uterine muscle which leads to fibroid.

 

LIST OF FIGURES

Figure 1 –     Uterine Fibroid

Figure 2 –    Hydrolysis of L-arginine

Figure 3 –    Structure of arginase and the active site

Figure 4 –    Showing the effect of sodium citrate on arginase from human fibroid tissue

Figure 5 –    Showing the effect of Glutathione (GSH) on arginase from human fibroid tissue.

 

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